Skeletal muscle fiber hypercontraction induced by Bothrops asper myotoxic phospholipases A(2) ex vivo does not involve a direct action on the contractile apparatus

Myonecrosis is a frequent clinical manifestation of envenomings by Viperidae snakes, mainly caused by the toxic actions of secreted phospholipase A(2) (sPLA(2)) enzymes and sPLA(2)-like homologs on skeletal muscle fibers. A hallmark of the necrotic process induced by these myotoxins is the rapid app...

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Detalles Bibliográficos
Autores principales: López-Dávila, Alfredo Jesús, Weber, Natalie, Nayak, Arnab, Fritz, Leon, Moustafa, Kian Rami, Gand, Luis Vincens, Wehry, Enke, Kraft, Theresia, Thum, Thomas, Fernández, Julián, Gutiérrez, José María, Lomonte, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Muscle Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499977/
https://www.ncbi.nlm.nih.gov/pubmed/37474774
http://dx.doi.org/10.1007/s00424-023-02840-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499977/
https://www.ncbi.nlm.nih.gov/pubmed/37474774
http://dx.doi.org/10.1007/s00424-023-02840-w

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