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Skeletal muscle fiber hypercontraction induced by Bothrops asper myotoxic phospholipases A(2) ex vivo does not involve a direct action on the contractile apparatus
Myonecrosis is a frequent clinical manifestation of envenomings by Viperidae snakes, mainly caused by the toxic actions of secreted phospholipase A(2) (sPLA(2)) enzymes and sPLA(2)-like homologs on skeletal muscle fibers. A hallmark of the necrotic process induced by these myotoxins is the rapid app...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499977/ https://www.ncbi.nlm.nih.gov/pubmed/37474774 http://dx.doi.org/10.1007/s00424-023-02840-w |