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Global impact of somatic structural variation on the cancer proteome

Both proteome and transcriptome data can help assess the relevance of non-coding somatic mutations in cancer. Here, we combine mass spectrometry-based proteomics data with whole genome sequencing data across 1307 human tumors spanning various tissues to determine the extent somatic structural varian...

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Detalles Bibliográficos
Autores principales: Chen, Fengju, Zhang, Yiqun, Chandrashekar, Darshan S., Varambally, Sooryanarayana, Creighton, Chad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499989/
https://www.ncbi.nlm.nih.gov/pubmed/37704602
http://dx.doi.org/10.1038/s41467-023-41374-8