Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma

Pilocytic astrocytoma (PA), the most common pediatric brain tumor, is driven by aberrant mitogen-activated protein kinase signaling most commonly caused by BRAF gene fusions or activating mutations. While 5-year overall survival rates exceed 95%, tumor recurrence or progression constitutes a major c...

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Detalles Bibliográficos
Autores principales: Picard, Daniel, Felsberg, Jörg, Langini, Maike, Stachura, Paweł, Qin, Nan, Macas, Jadranka, Reiss, Yvonne, Bartl, Jasmin, Selt, Florian, Sigaud, Romain, Meyer, Frauke-D., Stefanski, Anja, Stühler, Kai, Roque, Lucia, Roque, Rafael, Pandyra, Aleksandra A., Brozou, Triantafyllia, Knobbe-Thomsen, Christiane, Plate, Karl H., Roesch, Alexander, Milde, Till, Reifenberger, Guido, Leprivier, Gabriel, Faria, Claudia C., Remke, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500011/
https://www.ncbi.nlm.nih.gov/pubmed/37656187
http://dx.doi.org/10.1007/s00401-023-02626-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500011/
https://www.ncbi.nlm.nih.gov/pubmed/37656187
http://dx.doi.org/10.1007/s00401-023-02626-5

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