Major vault protein (MVP) suppresses aging- and estrogen deficiency-related bone loss through Fas-mediated apoptosis in osteoclasts

Osteoclasts (OCs), derived from monocyte/macrophage lineage, are key orchestrators in bone remodeling. Targeting osteoclast apoptosis is a promising approach to cut down excessive osteoclast numbers, and thus slow down the rate of bone mass loss that inevitably occurs during aging. However, the ther...

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Detalles Bibliográficos
Autores principales: Wang, Ruobing, Yang, Yan, Zhang, Zhongyin, Zhao, Na, Wiemer, Erik A. C., Ben, Jingjing, Ma, Junqing, Yuan, Lichan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500014/
https://www.ncbi.nlm.nih.gov/pubmed/37704623
http://dx.doi.org/10.1038/s41419-023-05928-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500014/
https://www.ncbi.nlm.nih.gov/pubmed/37704623
http://dx.doi.org/10.1038/s41419-023-05928-4

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