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Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA
The E. coli DEAD-Box helicase RhlB is responsible for ATP-dependent unwinding of structured mRNA to facilitate RNA degradation by the protein complex degradosome. The allosteric interaction with complex partner RNase E is necessary to stimulate both, RhlB’s ATPase and RNA unwinding activity to level...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500059/ https://www.ncbi.nlm.nih.gov/pubmed/37719267 http://dx.doi.org/10.3389/fmolb.2023.1139919 |