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Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA

The E. coli DEAD-Box helicase RhlB is responsible for ATP-dependent unwinding of structured mRNA to facilitate RNA degradation by the protein complex degradosome. The allosteric interaction with complex partner RNase E is necessary to stimulate both, RhlB’s ATPase and RNA unwinding activity to level...

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Detalles Bibliográficos
Autores principales: Zetzsche, Heidi, Raschke, Laura, Fürtig, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500059/
https://www.ncbi.nlm.nih.gov/pubmed/37719267
http://dx.doi.org/10.3389/fmolb.2023.1139919

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