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Genome-wide multimediator analyses using the generalized Berk–Jones statistics with the composite test

MOTIVATION: Mediation analysis is performed to evaluate the effects of a hypothetical causal mechanism that marks the progression from an exposure, through mediators, to an outcome. In the age of high-throughput technologies, it has become routine to assess numerous potential mechanisms at the genom...

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Detalles Bibliográficos
Autores principales: Lai, En-Yu, Huang, Yen-Tsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500087/
https://www.ncbi.nlm.nih.gov/pubmed/37665751
http://dx.doi.org/10.1093/bioinformatics/btad544