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Genome-wide multimediator analyses using the generalized Berk–Jones statistics with the composite test
MOTIVATION: Mediation analysis is performed to evaluate the effects of a hypothetical causal mechanism that marks the progression from an exposure, through mediators, to an outcome. In the age of high-throughput technologies, it has become routine to assess numerous potential mechanisms at the genom...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500087/ https://www.ncbi.nlm.nih.gov/pubmed/37665751 http://dx.doi.org/10.1093/bioinformatics/btad544 |