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Calcitonin gene-related peptide protects from soluble fms-like tyrosine kinase-1-induced vascular dysfunction in a preeclampsia mouse model

Introduction: Preeclampsia (PE) is a hypertensive disorder during pregnancy associated with elevated levels of soluble FMS-like tyrosine kinase (sFLT-1) and increased vascular sensitivity to angiotensin II (ATII). Calcitonin gene-related peptide (CALCA) is a potent vasodilator that inhibits the ATII...

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Detalles Bibliográficos
Autores principales: Mishra, Akansha, Betancourt, Ancizar, Vidyadharan, Vipin Alukkal, Blesson, Chellakkan Selvanesan, Belfort, Michael, Yallampalli, Chandra, Chauhan, Madhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500126/
https://www.ncbi.nlm.nih.gov/pubmed/37719463
http://dx.doi.org/10.3389/fphys.2023.1221684