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Cogs in the autophagic machine—equipped to combat dementia-prone neurodegenerative diseases
Neurodegenerative diseases are often characterized by hydrophobic inclusion bodies, and it may be the case that the aggregate-prone proteins that comprise these inclusion bodies are in fact the cause of neurotoxicity. Indeed, the appearance of protein aggregates leads to a proteostatic imbalance tha...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500130/ https://www.ncbi.nlm.nih.gov/pubmed/37720551 http://dx.doi.org/10.3389/fnmol.2023.1225227 |