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Exogenous Spermidine Alleviates Diabetic Myocardial Fibrosis Via Suppressing Inflammation and Pyroptosis in db/db Mice

BACKGROUND: The main pathological feature of diabetic cardiomyopathy (DCM) caused by diabetes mellitus is myocardial fibrosis. According to recent studies in cardiology, it has been suggested that spermidine (SPD) has cardioprotective properties. AIMS: To explore the role and mechanism of SPD in all...

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Detalles Bibliográficos
Autores principales: Wei, Can, Xu, Jiyu, Liu, Yong, Qadir, Javeria, Zhang, Shumin, Yuan, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500142/
https://www.ncbi.nlm.nih.gov/pubmed/37350700
http://dx.doi.org/10.4274/balkanmedj.galenos.2023.2023-3-102