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IGF2BP3 Enhances the Growth of Hepatocellular Carcinoma Tumors by Regulating the Properties of Macrophages and CD8(+) T Cells in the Tumor Microenvironment

BACKGROUND AND AIMS: Overexpression of IGF2BP3 is associated with the prognosis of hepatocellular carcinoma (HCC). However, its role in regulating tumor immune microenvironment (TME) is not well characterized. Here, we investigated the effects of IGF2BP3 on macrophages and CD8(+) T cells within the...

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Detalles Bibliográficos
Autores principales: Ma, Lingyu, Jiang, Jiayu, Si, Qin, Chen, Chong, Duan, Zhaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500288/
https://www.ncbi.nlm.nih.gov/pubmed/37719968
http://dx.doi.org/10.14218/JCTH.2023.00184