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Development and Validation of a Clinical Risk Score to Predict Immune-mediated Liver Injury Caused by Sintilimab: Assessed for Causality Using Updated RUCAM

BACKGROUND AND AIMS: Immune-mediated liver injury is a fatal side effect of sintilimab. This study aimed to shed light on the associated risk factors and characteristics of this adverse event. METHODS: The clinical records of 772 patients treated with sintilimab were retrospectively reviewed to inve...

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Detalles Bibliográficos
Autores principales: Zheng, Caiyun, Huang, Shunmin, Lin, Meimei, Hong, Baohui, Dai, Hengfen, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500293/
https://www.ncbi.nlm.nih.gov/pubmed/37719962
http://dx.doi.org/10.14218/JCTH.2023.00124