Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo

INTRODUCTION: Mucosal-associated invariant T (MAIT) cells are a population of innate-like T cells, which mediate host immunity to microbial infection by recognizing metabolite antigens derived from microbial riboflavin synthesis presented by the MHC-I-related protein 1 (MR1). Namely, the potent MAIT...

Descripción completa

Detalles Bibliográficos
Autores principales: Nelson, Adam G., Wang, Huimeng, Dewar, Phoebe M., Eddy, Eleanor M., Li, Songyi, Lim, Xin Yi, Patton, Timothy, Zhou, Yuchen, Pediongco, Troi J., Meehan, Lucy J., Meehan, Bronwyn S., Mak, Jeffrey Y. W., Fairlie, David P., Stent, Andrew W., Kjer-Nielsen, Lars, McCluskey, James, Eckle, Sidonia B. G., Corbett, Alexandra J., Souter, Michael N. T., Chen, Zhenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500299/
https://www.ncbi.nlm.nih.gov/pubmed/37720229
http://dx.doi.org/10.3389/fimmu.2023.1109759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500299/
https://www.ncbi.nlm.nih.gov/pubmed/37720229
http://dx.doi.org/10.3389/fimmu.2023.1109759

Ejemplares similares