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Structural and microstructural neuroimaging signature of C9orf72-associated ALS: A multiparametric MRI study

BACKGROUND: ALS patients with hexanucleotide expansion in C9orf72 are characterized by a specific clinical phenotype, including more aggressive disease course and cognitive decline. Computerized multiparametric MRI with gray matter volumetry and diffusion tensor imaging (DTI) to analyze white matter...

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Detalles Bibliográficos
Autores principales: Wiesenfarth, Maximilian, Huppertz, Hans-Jürgen, Dorst, Johannes, Lulé, Dorothée, Ludolph, Albert C., Müller, Hans-Peter, Kassubek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500452/
https://www.ncbi.nlm.nih.gov/pubmed/37696099
http://dx.doi.org/10.1016/j.nicl.2023.103505