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Structural and microstructural neuroimaging signature of C9orf72-associated ALS: A multiparametric MRI study
BACKGROUND: ALS patients with hexanucleotide expansion in C9orf72 are characterized by a specific clinical phenotype, including more aggressive disease course and cognitive decline. Computerized multiparametric MRI with gray matter volumetry and diffusion tensor imaging (DTI) to analyze white matter...
Autores principales: | Wiesenfarth, Maximilian, Huppertz, Hans-Jürgen, Dorst, Johannes, Lulé, Dorothée, Ludolph, Albert C., Müller, Hans-Peter, Kassubek, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500452/ https://www.ncbi.nlm.nih.gov/pubmed/37696099 http://dx.doi.org/10.1016/j.nicl.2023.103505 |
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