The enhancement of CRISPR/Cas9 gene editing using metformin

The CRISPR/Cas9 technology is a revolutionary tool that can be used to edit the genome. Specifically, the genome of hematopoietic stem cells (HSCs) could be edited to correct monogenic blood disorders as well as produce immunotherapies. However, the efficiency of editing HSCs remains low. To overcom...

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Detalles Bibliográficos
Autores principales: Rollins, Jaedyn L., Hall, Raquel M., Lemus, Clara J., Leisten, Lauren A., Johnston, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500454/
https://www.ncbi.nlm.nih.gov/pubmed/37720314
http://dx.doi.org/10.1016/j.bbrep.2023.101539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500454/
https://www.ncbi.nlm.nih.gov/pubmed/37720314
http://dx.doi.org/10.1016/j.bbrep.2023.101539

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