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Drug repurposing on Alzheimer's disease through modulation of NRF2 neighborhood

Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder and the most common cause of cognitive decline. The alarming epidemiological features of Alzheimer's disease, combined with the high failure rate of candidate drugs tested in the preclinical phase, impose more intense...

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Detalles Bibliográficos
Autores principales: Bourdakou, Marilena M., Fernández-Ginés, Raquel, Cuadrado, Antonio, Spyrou, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500459/
https://www.ncbi.nlm.nih.gov/pubmed/37696195
http://dx.doi.org/10.1016/j.redox.2023.102881