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Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues

[Image: see text] MurA catalyzes the first step of peptidoglycan (PG) biosynthesis and is a validated target for the development of new antimicrobial agents. In this study, a library of 49 plant flavonoids and their synthetic derivatives were evaluated for their inhibitory properties against MurA fr...

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Detalles Bibliográficos
Autores principales: Frlan, Rok, Hrast, Martina, Gobec, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500568/
https://www.ncbi.nlm.nih.gov/pubmed/37720776
http://dx.doi.org/10.1021/acsomega.3c04813