Cargando…
Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues
[Image: see text] MurA catalyzes the first step of peptidoglycan (PG) biosynthesis and is a validated target for the development of new antimicrobial agents. In this study, a library of 49 plant flavonoids and their synthetic derivatives were evaluated for their inhibitory properties against MurA fr...
Autores principales: | Frlan, Rok, Hrast, Martina, Gobec, Stanislav |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500568/ https://www.ncbi.nlm.nih.gov/pubmed/37720776 http://dx.doi.org/10.1021/acsomega.3c04813 |
Ejemplares similares
-
Inhibition of MurA Enzyme from Escherichia coli and Staphylococcus aureus by Diterpenes from Lepechinia meyenii and Their Synthetic Analogs
por: Funes Chabán, Macarena, et al.
Publicado: (2021) -
Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (–)-epicatechin
por: Rambaher, Martina Hrast, et al.
Publicado: (2023) -
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors
por: Ábrányi-Balogh, Péter, et al.
Publicado: (2022) -
Bromo-Cyclobutenaminones as New Covalent UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors
por: Hamilton, David J., et al.
Publicado: (2020) -
Design and Synthesis of Novel N-Benzylidenesulfonohydrazide Inhibitors of MurC and MurD as Potential Antibacterial Agents
por: Frlan, Rok, et al.
Publicado: (2008)