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Cholesterol and Ceramide Facilitate Membrane Fusion Mediated by the Fusion Peptide of the SARS-CoV-2 Spike Protein

[Image: see text] SARS-CoV-2 entry into host cells is mediated by the Spike (S) protein of the viral envelope. The S protein is composed of two subunits: S1 that induces binding to the host cell via its interaction with the ACE2 receptor of the cell surface and S2 that triggers fusion between viral...

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Detalles Bibliográficos
Autores principales: Niort, Kristina, Dancourt, Julia, Boedec, Erwan, Al Amir Dache, Zahra, Lavieu, Grégory, Tareste, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500581/
https://www.ncbi.nlm.nih.gov/pubmed/37720777
http://dx.doi.org/10.1021/acsomega.3c03610