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PD98059 protects SH-SY5Y cells against oxidative stress in oxygen–glucose deprivation/reperfusion

Mitochondria play a key role in the cerebral ischemia-reperfusion injury. Although the extracellular signal-regulated kinase 1/2 inhibitor PD98059 (PD) is a selective and reversible flavonoid that can protect the mitochondria in a rat model of cardiac arrest/cardiopulmonary resuscitation, its role r...

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Detalles Bibliográficos
Autores principales: Zhuge, Xiang-Zhen, Hu, Wan-Xiang, Liu, Yu-Mei, Jiang, Chang-Yue, Zhang, Xiao-Hua, Chen, Meng-Hua, Xie, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500637/
https://www.ncbi.nlm.nih.gov/pubmed/37719747
http://dx.doi.org/10.1515/tnsci-2022-0300