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Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP-Enhanced MAS NMR Spectroscopy of Proteins in Detergent Micelles

[Image: see text] Tremendous progress has been made in determining the structures of G-protein coupled receptors (GPCR) and their complexes in recent years. However, understanding activation and signaling in GPCRs is still challenging due to the role of protein dynamics in these processes. Here, we...

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Detalles Bibliográficos
Autores principales: Becker-Baldus, Johanna, Yeliseev, Alexei, Joseph, Thomas T., Sigurdsson, Snorri Th., Zoubak, Lioudmila, Hines, Kirk, Iyer, Malliga R., van den Berg, Arjen, Stepnowski, Sam, Zmuda, Jon, Gawrisch, Klaus, Glaubitz, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500644/
https://www.ncbi.nlm.nih.gov/pubmed/37720784
http://dx.doi.org/10.1021/acsomega.3c04681