Finding Lead Compounds for Dengue Antivirals from a Collection of Old Drugs through In Silico Target Prediction and Subsequent In Vitro Validation

[Image: see text] Dengue virus (DENV) infection is one of the most widely spread flavivirus infections. Despite the fatality it could cause, no antiviral treatment is currently available to treat the disease. Hence, this study aimed to repurpose old drugs as novel DENV NS3 inhibitors. Ligand-based (...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdullah, Zafirah Liyana, Chee, Hui-Yee, Yusof, Rohana, Mohd Fauzi, Fazlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500654/
https://www.ncbi.nlm.nih.gov/pubmed/37720780
http://dx.doi.org/10.1021/acsomega.3c02607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500654/
https://www.ncbi.nlm.nih.gov/pubmed/37720780
http://dx.doi.org/10.1021/acsomega.3c02607

Ejemplares similares