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Trichinella spiralis dipeptidyl peptidase 1 suppressed macrophage cytotoxicity by promoting M2 polarization via the STAT6/PPARγ pathway

Trichinella spiralis dipeptidyl peptidase 1 (TsDPP1), or cysteine cathepsin C, is a secretory protein that is highly expressed during the infective larvae and adult worm stages in the intestines. The aim of this study was to investigate the mechanism by which recombinant TsDPP1 (rTsDPP1) activates m...

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Detalles Bibliográficos
Autores principales: Yan, Shu Wei, Zhang, Ru, Guo, Xin, Wang, Bo Ning, Long, Shao Rong, Liu, Ruo Dan, Wang, Zhong Quan, Cui, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500742/
https://www.ncbi.nlm.nih.gov/pubmed/37705099
http://dx.doi.org/10.1186/s13567-023-01209-2