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TGFβ1-RCN3-TGFBR1 loop facilitates pulmonary fibrosis by orchestrating fibroblast activation

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) bears high mortality due to unclear pathogenesis and limited therapeutic options. Therefore, identifying novel regulators is required to develop alternative therapeutic strategies. METHODS: The lung fibroblasts from IPF patients and Reticulocalbin 3 (R...

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Detalles Bibliográficos
Autores principales: Wu, Mingting, Wang, Zhenyan, Shi, Xiaoqian, Zan, Danni, Chen, Hong, Yang, Shuqiao, Ding, Fangping, Yang, Liu, Tan, Pingping, Ma, Runlin Z., Wang, Jing, Ma, Lishuang, Ma, Yingmin, Jin, Jiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500825/
https://www.ncbi.nlm.nih.gov/pubmed/37710230
http://dx.doi.org/10.1186/s12931-023-02533-z