C-reactive protein binds to short phosphoglycan repeats of Leishmania secreted proteophosphoglycans and activates complement

Human C-reactive protein (CRP) binds to lipophosphoglycan (LPG), a virulence factor of Leishmania spp., through the repeating phosphodisaccharide region. We report here that both major components of promastigote secretory gel (PSG), the filamentous proteophosphoglycan (fPPG) and the secreted acid ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Seow, Eu Shen, Doran, Eve C., Schroeder, Jan-Hendrik, Rogers, Matthew E., Raynes, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500826/
https://www.ncbi.nlm.nih.gov/pubmed/37720216
http://dx.doi.org/10.3389/fimmu.2023.1256205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500826/
https://www.ncbi.nlm.nih.gov/pubmed/37720216
http://dx.doi.org/10.3389/fimmu.2023.1256205

Ejemplares similares