METTL14 is a chromatin regulator independent of its RNA N(6)-methyladenosine methyltransferase activity

METTL3 and METTL14 are two components that form the core heterodimer of the main RNA m(6)A methyltransferase complex (MTC) that installs m(6)A. Surprisingly, depletion of METTL3 or METTL14 displayed distinct effects on stemness maintenance of mouse embryonic stem cell (mESC). While comparable global...

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Detalles Bibliográficos
Autores principales: Dou, Xiaoyang, Huang, Lulu, Xiao, Yu, Liu, Chang, Li, Yini, Zhang, Xinning, Yu, Lishan, Zhao, Ran, Yang, Lei, Chen, Chuan, Yu, Xianbin, Gao, Boyang, Qi, Meijie, Gao, Yawei, Shen, Bin, Sun, Shuying, He, Chuan, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501186/
https://www.ncbi.nlm.nih.gov/pubmed/37030005
http://dx.doi.org/10.1093/procel/pwad009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501186/
https://www.ncbi.nlm.nih.gov/pubmed/37030005
http://dx.doi.org/10.1093/procel/pwad009

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