ORP8 acts as a lipophagy receptor to mediate lipid droplet turnover

Lipophagy, the selective engulfment of lipid droplets (LDs) by autophagosomes for lysosomal degradation, is critical to lipid and energy homeostasis. Here we show that the lipid transfer protein ORP8 is located on LDs and mediates the encapsulation of LDs by autophagosomal membranes. This function o...

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Detalles Bibliográficos
Autores principales: Pu, Maomao, Zheng, Wenhui, Zhang, Hongtao, Wan, Wei, Peng, Chao, Chen, Xuebo, Liu, Xinchang, Xu, Zizhen, Zhou, Tianhua, Sun, Qiming, Neculai, Dante, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501187/
https://www.ncbi.nlm.nih.gov/pubmed/37707322
http://dx.doi.org/10.1093/procel/pwac063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501187/
https://www.ncbi.nlm.nih.gov/pubmed/37707322
http://dx.doi.org/10.1093/procel/pwac063

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