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Incidence and prognostic impact of U2AF1 mutations and other gene alterations in myelodysplastic neoplasms with isolated 20q deletion

BACKGROUND: In myelodysplastic neoplasms (MDS), the 20q deletion [del(20q)] is a recurrent chromosomal abnormality that it has a high co‐occurrence with U2AF1 mutations. Nevertheless, the prognostic impact of U2AF1 in these MDS patients is uncertain and the possible clinical and/or prognostic differ...

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Detalles Bibliográficos
Autores principales: Castillo, Martín I., Ribate, Villamón E., Muñoz, Calabuig M., Santillana, Sanz G., Taboada, Such E., Casterá, Mora E., Abinzano, Calasanz M. J., Barranco, Irigoyen A., Nieto, Collado R., Pampliega, Vara M., Blanco, M. L., de Andrés, Álvarez S., de Oteyza, Pérez J., del Castillo, Bernal T., Font, Granada I., Cayuela, Jerez A., Díez‐Campelo, M., Sánchez, Abellán R., Vercet, Solano C., Díaz, Tormo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501246/
https://www.ncbi.nlm.nih.gov/pubmed/37403747
http://dx.doi.org/10.1002/cam4.6300