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Concordance in detection of microsatellite instability by PCR and NGS in routinely processed tumor specimens of several cancer types

BACKGROUND: Microsatellite instability (MSI) occurs in several cancer types and is commonly used for prognosis and as a predictive biomarker for immune checkpoint therapy. METHODS: We analyzed n = 263 formalin‐fixed paraffin‐embedded (FFPE) tumor specimens (127 colorectal cancer (CRC), 55 endometria...

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Detalles Bibliográficos
Autores principales: Bartels, Stephan, Grote, Isabel, Wagner, Madeleine, Boog, Jannik, Schipper, Elisa, Reineke‐Plaass, Tanja, Kreipe, Hans, Lehmann, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501280/
https://www.ncbi.nlm.nih.gov/pubmed/37376830
http://dx.doi.org/10.1002/cam4.6293