MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells

Chondrosarcomas and osteosarcomas are malignant bone tumors with a poor prognosis when unresectable or metastasized. Moreover, radiotherapy and chemotherapy could be ineffective. MiRNAs represent an alternative therapeutic approach. Based on high-throughput functional screening, we identified four m...

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Detalles Bibliográficos
Autores principales: Veys, Clément, Boulouard, Flavie, Benmoussa, Abderrahim, Jammes, Manon, Brotin, Emilie, Rédini, Françoise, Poulain, Laurent, Gruchy, Nicolas, Denoyelle, Christophe, Legendre, Florence, Galera, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501397/
https://www.ncbi.nlm.nih.gov/pubmed/37719019
http://dx.doi.org/10.3389/fonc.2023.1220459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501397/
https://www.ncbi.nlm.nih.gov/pubmed/37719019
http://dx.doi.org/10.3389/fonc.2023.1220459

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