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MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells
Chondrosarcomas and osteosarcomas are malignant bone tumors with a poor prognosis when unresectable or metastasized. Moreover, radiotherapy and chemotherapy could be ineffective. MiRNAs represent an alternative therapeutic approach. Based on high-throughput functional screening, we identified four m...
Autores principales: | Veys, Clément, Boulouard, Flavie, Benmoussa, Abderrahim, Jammes, Manon, Brotin, Emilie, Rédini, Françoise, Poulain, Laurent, Gruchy, Nicolas, Denoyelle, Christophe, Legendre, Florence, Galera, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501397/ https://www.ncbi.nlm.nih.gov/pubmed/37719019 http://dx.doi.org/10.3389/fonc.2023.1220459 |
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