Exploration of 2D and 3D-QSAR analysis and docking studies for novel dihydropteridone derivatives as promising therapeutic agents targeting glioblastoma

Background: Dihydropteridone derivatives represent a novel class of PLK1 inhibitors, exhibiting promising anticancer activity and potential as chemotherapeutic drugs for glioblastoma. Objective: The aim of this study is to develop 2D and 3D-QSAR models to validate the anticancer activity of dihydrop...

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Detalles Bibliográficos
Autores principales: Pan, Meichen, Cheng, Lingxue, Wang, Yiguo, Lyu, Chunyi, Hou, Chao, Zhang, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501407/
https://www.ncbi.nlm.nih.gov/pubmed/37719847
http://dx.doi.org/10.3389/fphar.2023.1249041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501407/
https://www.ncbi.nlm.nih.gov/pubmed/37719847
http://dx.doi.org/10.3389/fphar.2023.1249041

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