Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis

Exocrine cells utilize large secretory vesicles (LSVs) up to 10 μm in diameter. LSVs fuse with the apical surface, often recruiting actomyosin to extrude their content through dynamic fusion pores. The molecular mechanism regulating pore dynamics remains largely uncharacterized. We observe that the...

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Detalles Bibliográficos
Autores principales: Biton, Tom, Scher, Nadav, Carmon, Shari, Elbaz-Alon, Yael, Schejter, Eyal D., Shilo, Ben-Zion, Avinoam, Ori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501449/
https://www.ncbi.nlm.nih.gov/pubmed/37707500
http://dx.doi.org/10.1083/jcb.202302112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501449/
https://www.ncbi.nlm.nih.gov/pubmed/37707500
http://dx.doi.org/10.1083/jcb.202302112

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