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Unraveling the impact of disrupted nucleocytoplasmic transport systems in C9orf72-associated ALS
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two adult-onset neurodegenerative diseases that are part of a common disease spectrum due to clinical, genetic, and pathological overlap. A prominent genetic factor contributing to both diseases is a hexanucleotide repeat expa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501458/ https://www.ncbi.nlm.nih.gov/pubmed/37720544 http://dx.doi.org/10.3389/fncel.2023.1247297 |