Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner

INTRODUCTION: Soluble antigens complexed with immunoglobulin G (IgG) antibodies can induce robust adaptive immune responses in vitro and in animal models of disease. Factor VIII immune complexes (FVIII-ICs) have been detected in individuals with hemophilia A and severe von Willebrand disease followi...

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Detalles Bibliográficos
Autores principales: Batsuli, Glaivy, Ito, Jasmine, York, Elizabeth S., Cox, Courtney, Baldwin, Wallace, Gill, Surinder, Lollar, Pete, Meeks, Shannon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501482/
https://www.ncbi.nlm.nih.gov/pubmed/37720212
http://dx.doi.org/10.3389/fimmu.2023.1233356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501482/
https://www.ncbi.nlm.nih.gov/pubmed/37720212
http://dx.doi.org/10.3389/fimmu.2023.1233356

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