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A prospective study to assess the role of paraoxonase 1 genotype and phenotype on the lipid-lowering and antioxidant activity of statins

Human paraoxonase 1 (PON1) enzyme protects against atherosclerosis by preventing low-density lipoprotein from oxidative modification. Upregulation of PON1 enzymatic activity is suggested to contribute to atheroprotective potential of statins. Glutamine (Q) to arginine (R) at site 192 and leucine (L)...

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Detalles Bibliográficos
Autores principales: Godbole, Charuta, Thaker, Saket, Salagre, Santosh, Shivane, Vyankatesh, Gogtay, Nithya, Thatte, Urmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501533/
https://www.ncbi.nlm.nih.gov/pubmed/37555413
http://dx.doi.org/10.4103/ijp.IJP_215_20