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A prospective study to assess the role of paraoxonase 1 genotype and phenotype on the lipid-lowering and antioxidant activity of statins
Human paraoxonase 1 (PON1) enzyme protects against atherosclerosis by preventing low-density lipoprotein from oxidative modification. Upregulation of PON1 enzymatic activity is suggested to contribute to atheroprotective potential of statins. Glutamine (Q) to arginine (R) at site 192 and leucine (L)...
Autores principales: | Godbole, Charuta, Thaker, Saket, Salagre, Santosh, Shivane, Vyankatesh, Gogtay, Nithya, Thatte, Urmila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501533/ https://www.ncbi.nlm.nih.gov/pubmed/37555413 http://dx.doi.org/10.4103/ijp.IJP_215_20 |
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