Genetic polymorphisms of microsomal epoxide hydrolase and UDP-glucuronosyltransferase (UGT) and its effects on plasma carbamazepine levels and metabolic ratio in persons with epilepsy of South India: A cross-sectional genetic association study

OBJECTIVES: Carbamazepine (CBZ), an anti-seizure drug, is widely prescribed for the management of focal seizures. At a given therapeutic dose, CBZ exhibits marked interindividual variation in the plasma CBZ levels. The aim wasto study the influence of EPHX1 c.337 T>C and UGT2B7*2 genetic polymorp...

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Detalles Bibliográficos
Autores principales: Venkatraman, Shravan, Ramasamy, Kesavan, Nair, Pradeep Pankajakshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501538/
https://www.ncbi.nlm.nih.gov/pubmed/37555408
http://dx.doi.org/10.4103/ijp.ijp_228_22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501538/
https://www.ncbi.nlm.nih.gov/pubmed/37555408
http://dx.doi.org/10.4103/ijp.ijp_228_22

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