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Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism
Tetrahymena are ciliated protists that have been used to study the effects of toxic chemicals, including anticancer drugs. In this study, we tested the inhibitory effects of six pyrimidine analogs (5-fluorouracil, floxuridine, 5’-deoxy-5-fluorouridine, 5-fluorouridine, gemcitabine, and cytarabine) o...
Autores principales: | Harpel, Zander, Chang, Wei-Jen, Circelli, Jacob, Chen, Richard, Chang, Ian, Rivera, Jason, Wu, Stephanie, Wei, RongHan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501602/ https://www.ncbi.nlm.nih.gov/pubmed/37708236 http://dx.doi.org/10.1371/journal.pone.0284309 |
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