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RSim: A reference-based normalization method via rank similarity
Microbiome sequencing data normalization is crucial for eliminating technical bias and ensuring accurate downstream analysis. However, this process can be challenging due to the high frequency of zero counts in microbiome data. We propose a novel reference-based normalization method called normaliza...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501661/ https://www.ncbi.nlm.nih.gov/pubmed/37656740 http://dx.doi.org/10.1371/journal.pcbi.1011447 |