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Extracellular vesicles as a potential source of tumor-derived DNA in advanced pancreatic cancer

Tumor-derived extracellular vesicles (EVs) are reported to contain nucleic acids, including DNA. Several studies have highlighted the potential of EV-derived DNA (evDNA) as a circulating biomarker, even demonstrating that evDNA can outperform cell-free DNA (cfDNA) in terms of sensitivity. Here, we e...

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Detalles Bibliográficos
Autores principales: Lapin, Morten, Tjensvoll, Kjersti, Nedrebø, Karoline, Taksdal, Eline, Janssen, Hans, Gilje, Bjørnar, Nordgård, Oddmund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501680/
https://www.ncbi.nlm.nih.gov/pubmed/37708210
http://dx.doi.org/10.1371/journal.pone.0291623