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A structural classification of the variant surface glycoproteins of the African trypanosome

Long-term immune evasion by the African trypanosome is achieved through repetitive cycles of surface protein replacement with antigenically distinct versions of the dense Variant Surface Glycoprotein (VSG) coat. Thousands of VSG genes and pseudo-genes exist in the parasite genome that, together with...

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Detalles Bibliográficos
Autores principales: Đaković, Sara, Zeelen, Johan P., Gkeka, Anastasia, Chandra, Monica, van Straaten, Monique, Foti, Konstantina, Zhong, Janet, Vlachou, Evi P., Aresta-Branco, Francisco, Verdi, Joseph P., Papavasiliou, F. Nina, Stebbins, C. Erec
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501684/
https://www.ncbi.nlm.nih.gov/pubmed/37656766
http://dx.doi.org/10.1371/journal.pntd.0011621