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Pancreatic β-cell senescence in diabetes: mechanisms, markers and therapies

Cellular senescence is a response to a wide variety of stressors, including DNA damage, oncogene activation and physiologic aging, and pathologically accelerated senescence contributes to human disease, including diabetes mellitus. Indeed, recent work in this field has demonstrated a role for pancre...

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Detalles Bibliográficos
Autores principales: Cha, Jeeyeon, Aguayo-Mazzucato, Cristina, Thompson, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501801/
https://www.ncbi.nlm.nih.gov/pubmed/37720527
http://dx.doi.org/10.3389/fendo.2023.1212716