Self-assembly of CXCR4 antagonist peptide–docetaxel conjugates for breast tumor multi-organ metastasis inhibition

As a representative chemotherapeutic drug, docetaxel (DTX) has been used for breast cancer treatment for decades. However, the poor solubility of DTX limits its efficacy, and the DTX based therapy increases the metastasis risk due to the upregulation of C–X–C chemokine receptor type 4 (CXCR4) expres...

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Detalles Bibliográficos
Autores principales: Li, Chen, Lang, Jiayan, Wang, Yazhou, Cheng, Zhaoxia, Zu, Mali, Li, Fenfen, Sun, Jingyi, Deng, Yating, Ji, Tianjiao, Nie, Guangjun, Zhao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501865/
https://www.ncbi.nlm.nih.gov/pubmed/37719382
http://dx.doi.org/10.1016/j.apsb.2023.03.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501865/
https://www.ncbi.nlm.nih.gov/pubmed/37719382
http://dx.doi.org/10.1016/j.apsb.2023.03.024

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