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Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly

Depsides and depsidones have attracted attention for biosynthetic studies due to their broad biological activities and structural diversity. Previous structure‒activity relationships indicated that triple halogenated depsidones display the best anti-pathogenic activity. However, the gene cluster and...

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Detalles Bibliográficos
Autores principales: Yang, Jiafan, Zhou, Zhenbin, Chen, Yingying, Song, Yongxiang, Ju, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501868/
https://www.ncbi.nlm.nih.gov/pubmed/37719379
http://dx.doi.org/10.1016/j.apsb.2023.05.036