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Tubular lysosome induction couples animal starvation to healthy aging

Dietary restriction promotes longevity in several species via autophagy activation. However, changes to lysosomes underlying this effect remain unclear. Here using the nematode Caenorhabditis elegans, we show that the induction of autophagic tubular lysosomes (TLs), which occurs upon dietary restric...

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Detalles Bibliográficos
Autores principales: Villalobos, Tatiana V., Ghosh, Bhaswati, DeLeo, Kathryn R., Alam, Sanaa, Ricaurte-Perez, Cristian, Wang, Andrew, Mercola, Brennan M., Butsch, Tyler J., Ramos, Cara D., Das, Suman, Eymard, Eric D., Bohnert, K. Adam, Johnson, Alyssa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501908/
https://www.ncbi.nlm.nih.gov/pubmed/37580394
http://dx.doi.org/10.1038/s43587-023-00470-6