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Tubular lysosome induction couples animal starvation to healthy aging
Dietary restriction promotes longevity in several species via autophagy activation. However, changes to lysosomes underlying this effect remain unclear. Here using the nematode Caenorhabditis elegans, we show that the induction of autophagic tubular lysosomes (TLs), which occurs upon dietary restric...
Autores principales: | Villalobos, Tatiana V., Ghosh, Bhaswati, DeLeo, Kathryn R., Alam, Sanaa, Ricaurte-Perez, Cristian, Wang, Andrew, Mercola, Brennan M., Butsch, Tyler J., Ramos, Cara D., Das, Suman, Eymard, Eric D., Bohnert, K. Adam, Johnson, Alyssa E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501908/ https://www.ncbi.nlm.nih.gov/pubmed/37580394 http://dx.doi.org/10.1038/s43587-023-00470-6 |
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