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When gold standards are not so golden: prevalence bias in randomized trials on endoscopic colorectal cancer screening

Randomized trials on the effectiveness of screening endoscopy in reducing colorectal cancer (CRC) risk have reported statistically significant, but rather modest reduction of CRC risk by the screening offer. However, risk estimates in these trials included substantial proportions of prevalent CRC ca...

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Detalles Bibliográficos
Autores principales: Brenner, Hermann, Heisser, Thomas, Cardoso, Rafael, Hoffmeister, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10501935/
https://www.ncbi.nlm.nih.gov/pubmed/37530938
http://dx.doi.org/10.1007/s10654-023-01031-2